Fungal infection in acute leukemia

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Hepatosplenic fungal infection in adult patients with acute leukemia.

BACKGROUND Hepatosplenic fungal infection is an important infectious complication in adult patients with acute leukemia. METHODS From 2001 to 2004, 163 adult patients were diagnosed with acute leukemia at our center: 41 patients had acute lymphoblastic leukemia (ALL) and 122 patients had acute myeloid leukemia (AML). Their charts were retrospectively reviewed. RESULTS Of these 163 patients,...

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BACKGROUND Invasive fungal infections (IFIs) are a life-threatening problem in immunocompromised patients. Despite timely diagnosis and appropriate antifungal therapy, clinical outcomes of IFIs remain unsatisfactory, necessitating treatment with a combination of antifungal agents. Therefore, childhood leukemic patients treated with voriconazole plus caspofungin were evaluated for the safety and...

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ژورنال

عنوان ژورنال: Cancer

سال: 1972

ISSN: 0008-543X,1097-0142

DOI: 10.1002/1097-0142(197208)30:2<348::aid-cncr2820300207>3.0.co;2-o